Fontana, B.D., Müller, T.E., Cleal, M., de Abreu, M.S., Norton, W.H.J, Demin, K.A., Amstislavskaya, T.G., Petersen, E.V., Kalueff, A.V., Parker, M.O., Rosemberg, D.B. (2022). Using zebrafish (Danio rerio) models to understand the critical role of social interactions in mental health and wellbeing. Progress in Neurobiology. (Available online). 


Whitehouse, J., Milward, S.J., Parker, M.O., Kavanagh, E., Waller, B.M. (2022). Signal value of stress behaviour. Evolution and Human Behavior. (Available online).  



Fontana, B.D., Alnassar, N. , Parker, M.O. (2022). The zebrafish (Danio rerio) anxiety test battery: Comparison of behavioral responses in the novel tank diving and light-dark tasks following exposure to anxiogenic and anxiolytic compounds. Psychopharmacology. (Available online). 




Fontana, B.D., Alnassar, N., Parker, M.O. (2021). The impact of water changes on stress and subject variation in a zebrafish (Danio rerio) anxiety-related task. Journal of Neuroscience Methods. Available online. 


Fontana, B.D., Alnassar, N., Parker, M.O. (2021). Tricaine methanesulfonate (MS222) has short-term effects on young adult zebrafish (Danio rerio) working memory and cognitive flexibility, but not on aging fish. Frontiers in Behavioural Neuroscience. (Available online).


Cleal, M., Fontana, B.D., Double, M., Mezabrovschi, R., Parcell, L., Redhead, E., Parker, M.O. (2021) Dopaminergic Modulation of Working Memory and Cognitive Flexibility in a Zebrafish Model of Aging-Related Cognitive Decline. Neurobiology of Aging, 102, 1-16. Available from Biorxiv doi: 


Fontana, B.D., Cleal, M., McBride, S.D., Gibbon, A., Parker, M.O. (2021). The effects of two stressors on working memory and cognitive flexibility in zebrafish (Danio rerio): The protective role of D1/D5 agonist on stress responses. Neuropharmacology. (Available online). 

Cleal, M., Fontana, B.D., Parker, M.O. (2021). The Cognitive and Behavioral Effects of D-Amphetamine and Nicotine Sensitization in Adult Zebrafish. Psychopharmacology. (Available online). 


Kohler, S., Parker, M.O., Ford, A. (2021). High-throughput screening of psychotropic compounds: impacts on swimming behaviours in Artemia franciscana. Toxics, 9, 64.


Fontana, B.D., Gibbon, A.J., Cleal, M., Sudwarts, A., Pritchett, D., Petrazzini, M.E.M., Brennan, C.H., Parker, M.O. (2021). Moderate early-life stress improves adult zebrafish (Danio rerio) working memory but does not affect social and anxiety-like responses. Developmental Psychobiology, 63, 54-64. Doi: 


Clay, J.M., Stafford, L.D., Parker, M.O. (2021) Associations between self-reported inhibitory control, stress, and alcohol (mis)use during the first wave of the COVID-19 pandemic in the UK: a national cross-sectional study utilising data from four birth cohorts. International Journal of Mental Health and Addiction. Available from medRxiv 


Fontana, B.D., Parker, M.O., Norton, W.H.J. (2021). Modelling ADHD-like phenotypes in zebrafish. In: S.C. Stanford & E. Sciberras (Eds.). New Discoveries in the Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder. Springer Nature, Switzerland.






Cleal, M., Gibbon, A.J., Fontana, B.D, Parker, M.O. (2020). The importance of pH: how aquarium water is affecting behavioural responses to drug exposure in larval zebrafish. Pharmacology, Biochemistry and Behavior (Available online)


Fontana, B.D., Gibbon, A.J., Cleal, M., Norton, W.H.J., Parker, M.O. (2020). Chronic unpredictable early-life stress (CUELS) protocol: early-life stress changes anxiety levels of adult zebrafish. Progress in Neuropsychopharmacology & Biological Psychiatry. (Available online)


Cleal, M., Fontana, B.D, Ranson, D.C., McBride, S.D., Swinny, J.D., Redhead, E.S., Parker, M.O. (2020). The Free-Movement Pattern Y-Maze: The Effective Study Of Working Memory, Exploratory Patterns And Behavioural Plasticity. Behavior Research Methods. (Available online) 


de Abreu, M.S., Giacomini, A.C.C.V., Genario, R., Marcon, L., Scolari, N., Bueno, B., Fontana, B.D., Parker, M.O., Demin, K., Kalueff, A.V. (2020). Zebrafish models of impulsivity and impulse control disorders. European Journal of Neuroscience. (Available online)


Parker, M.O. (2020). Module 11: The care and use of animals in research. Research Integrity, UK (2nd Ed). Oxford University Press


Fontana, B.D, Gibbon, A.J, Cleal, M., Sudwarts, A., Pritchett, D., Petrazzini, M.E.M., Brennan, C.H., Parker, M.O. (2020). Moderate early-life stress improves adult zebrafish (Danio rerio) working memory but does not affect social and anxiety-like responses. Developmental Psychobiology. Available Online.


Clay, J. M., & Parker, M. O. (2020). Alcohol use and misuse during the COVID19 pandemic: a potential public health crisis? The Lancet Public Health. Available online.


García-González, J., Brock, A.J., Parker, M.O., Riley, R., Jolliffe, D., Sudwarts, A., Teh, M-T., Busch-Nentwich, E.M., Stemple, D.L., Martineau, A.R., Kaprio, J., Palviainen, T., Kuan, V., Walton, R.T., Brennan, C.H. (2020). Identification of Slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour. eLife. Available online.


Muller, T.E., Fontana, B.D., Bertoncello, K.T., Franscescon,F., Mezzomo, N.J., Canzian, J., Stefanello, F.V., Parker, M.O., Gerlai, R., Rosemberg D.B. (2020). Understanding the neurobiological effects of drug abuse: lessons from zebrafish models. Progress in Neuro-Psychopharmacology and Biological Psychiatry. Available online.




Demin, K.A., Lakstygal, A.M., Volgin, A.D., de Abreu, M.S., Genario, R., Alpyshov, E.T., Serikuly, N., Wang, D., Wang, J., Yan, D., Wang, M., Yang, L., Hu, G., Bytov, M., Zabegalov, K.A., Zhdanov, K., Harvey, B.H., Costa, F., Rosemberg, D.B., Leonard, B.E., Fontana, B.D., Cleal, M., Parker, M.O., Wang, J., Song, C., Amstislavskaya, T.G., Kalueff, A.V. (2019). Cross-species analyses of intra-species behavioral differences in mammals and fish. Neuroscience. Available Online. 


Fontana, B.D., Duarte, T., Müller, T.E., Canzian, J., Ziani, P.R., Mezzomo, N.J., Parker, M.O., Rosemberg, D.B. (2019). Concomitant taurine exposure counteracts ethanol-induced changes in locomotor and anxiety-like responses in zebrafish. Psychopharmacology. Available online.


Gutierrez, H.C., Vacca, I., Schoenmaker, G., Cleal, M., Tochwin, A., O’Connor, B., Young, A.M.J., Vasquez, A.A., Winter, M.J., Parker, M.O., Norton, W.H.J. (2019). Screening for drugs to reduce zebrafish aggression identifies caffeine and sildenafil. European Neuropsychopharmacology. Available online as free download.


Fontana, B.D., Cleal, M., Parker, M.O. (2019). Female adult zebrafish (Danio rerio) show higher levels of anxiety-like behavior than males, but do not differ in learning and memory capacity. European Journal of Neuroscience. Available online. 


Fontana, B.D., Cleal, M., Clay, J.M., Parker, M.O. (2019). Zebrafish (Danio rerio) behavioral laterality predicts increased short-term avoidance memory but not stress-reactivity responses. Animal Cognition. Download link -


Stafford, L.D., Damant, K., Ashusrt, S., Parker, M.O. (2019). Higher olfactory sensitivity to coffee odour in habitual caffeine users. Experimental and Clinical Psychopharmacology. Available online.


Zabegalova, K.N., Khatskob, S.L., Lakstygac, A.M., Deminc, K.A., Cleal, M., Dotto Fontana, B., McBride, S.D., Harvey, B.H., de Abreul, M.S., Parker M.O., Kalueff, A.V. (2019). Abnormal repetitive behaviors in zebrafish and their relevance to human brain disorders. Behavioural Brain Research. Available online. 


Fontana, B.D., Franscescon, F., Rosemberg, D.B., Norton, W.H.J., Kalueff, A.V., Parker M.O. (2019). Zebrafish models for attention deficit hyperactivity disorder (ADHD). Neuroscience and Biobehavioral Reviews, Available online 


Demin, K.A., Sysoev, M., Wappler-Guzzetta, E., Koshiba, M., Oksenkrug, G.,  Song, C., Leonard, B., Parker, M.O., Harvey, B., Tiant, L., Strekalovav, T.V. Kalueff, A.V. (2019). Animal models of major depressive disorder and the implications for drug discovery and development, Expert Opinion on Drug Discovery, Available online.



Cleal, M., Parker, M.O. (In press). Moderate developmental alcohol exposure reduces repetitive alternation in a zebrafish model of fetal alcohol spectrum disorders, Neurotoxicology and Teratology. 


Clay, J.M., & Parker, M.O. (2018) The role of stress-reactivity, stress-recovery and risky decision- making in psychosocial stress-induced alcohol consumption in social drinkers. Psychopharmacology


Fontana, B.D., Stefanello, F.V., Mezzomo, N.J., Müller, T.E., Quadros, V.A., Parker, M.O., Rico, E.P., Rosemberg, D.B. (2018). Taurine modulates acute ethanol-induced social behavioral deficits and fear responses in adult zebrafish. Journal of Psychiatric Research,104,176-182.


Koeler, S., Parker., M.O., Ford, A. (2018). Species-specific behaviours in amphipods highlight the need for understanding baseline behaviours in ecotoxicology. Aquatic Toxicology, 202, 173-180.


Koeler, S., Parker., M.O., Ford, A. (2018). Shape and size of the arenas affect amphipod behaviours: implications for ecotoxicology, PeerJ,  6, e5271.


Hemmings, A.J., Parker, M.O., Hale, C., McBride, S.D. (2018). Causal and functional interpretation of mu- and delta-opioid receptor profiles in mesoaccumbens and nigrostriatal pathways of an oral stereotypy phenotype. Behavioural Brain Research, 353, 108-113.


Clay, J.M., Adams, C., Archer, P, English, M., Hyde, A., Stafford, L.D., Parker, M.O.(2018). Psychosocial stress increases craving for alcohol in social drinkers: effects of risk-taking. Drug and Alcohol Dependence, 185, 192-197. 




Omidi, A, Jafari, R, Nazifi, S, Parker, M.O. (2017). Potential role of selenium in the pathophysiology of crib-biting behavior in horses. Journal of Veterinary Behavior: Clinical Applications and Research, Available online.


Brock, A. J., Goody, S. M. G., Mead, A.N., Sudwarts, A., Parker, M.O. & Brennan, C.H (2017). Assessing the value of the zebrafish conditioned place preference model for predicting human abuse potential. Journal of Pharmacology and Experimental Therapeutics, AVAILABLE ONLINE.


Brock, A.J., Sudwarts, A., Daggett, J., Parker, M.O., Brennan, C.H. (2017). A fully automated computer based Skinner box for testing learning and memory in zebrafish. bioRxiv, p.110478.


Roberts, K., Hemmings, A.J., McBride, S.D., Parker, M.O. (2017). Causal Factors of Oral versus Locomotor Stereotypy in the Horse. Journal of Veterinary Behavior: Clinical Applications and Research, 20, 37–43.


Roberts, K., Hemmings, A.J., McBride, S.D., Parker, M.O. (2017). Developing a 3-choice serial reaction time task for examining neural and cognitive function in an equine model. Journal of Neuroscience Methods.


Omidi, A., Fathi, M.H., Parker, M.O. (2017). Alterations of antioxidant status markers in dairy cows during lactation and in the dry period. Journal of Dairy Research, 84, 49-53.


McBride, S.D., Parker, M.O., Roberts, K., Hemmings, A. (2017). Applied neurophysiology of the horse: implications for training, husbandry and welfare. Applied Animal Behaviour Science, 190, 90-101.




Brock, A. J., Sudwarts, A., Parker, M.O., Brennan, C.H. (2016). Zebrafish behavioral models of ageing. In: A.V. Kalueff (Ed.)The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish. Springer Publishing.


Parker, M.O. (2016). Modeling OCD endophenotypes in zebrafish. In: A.V. Kalueff (Ed.) The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish. Springer Publishing.


Roberts, K., Hemmings, A.J., Moore-Colyer, M., Parker, M.O., McBride, S.D. (2016). Neural Modulators of Temperament: a multivariate approach to personality trait identification in the horse. Physiology & Behavior, 167, 125-131.


Omidi, A., Vakili, S., Nazifi, S., Parker, M.O. (2016). Acute-phase proteins, oxidative stress and antioxidant defense in crib-biting horses. Journal of Veterinary Behavior: Clinical Applications and Research, 20, 31–36.


Parker, M.O., Brennan, C.H. (2016). Translational pharmacology of a putative measure of motor impulsivity in larval zebrafish. Current Psychopharmacology, 5, 73-84.


Homberg, J.R., et al. (2016). Genetic and environmental modulation of neurodevelopmental disorders: translational insights from labs to beds. Brain Research Bulletin, 125, 79-91.


Homberg, J.R., et al. (2016). Understanding autism and other neurodevelopmental disorders through experimental translational neurobehavioral models. Neuroscience and Biobehavioural Reviews, 65, 292-312.


Mazelet, L., Parker, M. O., Li, M., Anders, A., Ashworth, R. (2016). Role of active contraction and tropomodulins in regulating actin filament length and sarcomere structure in developing zebrafish skeletal muscle. Frontiers in Physiology,7:91.


Baiamonte, M., Parker, M.O., Vinson, G.P., Brennan, C.H. (2016). Sustained effects of developmental exposure to ethanol on zebrafish anxiety-like behaviour. PLoS ONE, 11(2), e0148425.


Homberg, J.R., et al. (2016). Improving treatment of neurodevelopmental disorders: recommendations based on preclinical studies. Expert Opinion on Drug Discovery, 11(1), 11-25.


Parker, M.O. (2016). Adult vertebrate behavioural aquatic toxicology: reliability and ecological validity. Aquatic Toxicology,170, 323-329.


Parker, M.O., Evans, A. M-D., Brock, A.J., Combe, F.J., Teh, M-T., Brennan, C.H. (2016). Developmental exposure to moderate levels of ethanol increases habit formation in a zebrafish model of foetal alcohol spectrum disorder. Addiction Biology, 21, 49-60.




Parker, M.O., Brock, A.J., Sudwarts, A., Teh, M-T., Combe, F.J., Brennan, C.H. (2015). Developmental role of acetylcholinesterase in impulse control in zebrafish. Frontiers in Behavioral Neuroscience. 9:271.


Kalueff, A.V., Stewart, A., Ullmann, J., Norton, W., Brennan, C.H., Parker, M.O., Gerlai, R. (2015). Molecular psychiatry of zebrafish. Molecular Psychiatry, 20, 2-17.


McBride, S.D., Parker, M.O. (2015). The disrupted basal ganglia and behavioural control: an insight from spontaneous stereotypy. Behavioural Brain Research, 276, 45-58.




Proulx, M.J., Parker, M.O., Tahir. Y., Brennan, C.H. (2014). Parallel mechanisms for visual search in zebrafish. PLoS ONE, 9,e111540.


Parker, M.O., Annan, L., Kanoupopolous, A., Brock, A.J., Baiamonte, M., Teh, M-T., Brennan, C.H. (2014). The utility of zebrafish to study the mechanisms by which ethanol affects social behavior and anxiety during early brain development.Progress in Neuropsychopharamcology and Biological Psychiatry, 55, 94-100.


Parker, M.O., Brock, A.J., Sudwarts, A., Brennan, C.H. (2014). Atomoxetine reduces anticipatory responding in a 5-choice serial reaction time task for adult zebrafish. Psychopharmacology, 231, 2671–2679.




Parker, M.O., Brock, A.J., Millington, M.E., Brennan, C.H. (2013). Behavioural phenotyping of casper mutant and 1-pheny-2-thiourea treated adult zebrafish. Zebrafish, 10, 466-471.


Jamieson, J., Reiss, M.J., Allen, D., Asher, L., Parker, M.O., Wathes, C.M., & Abeyesinghe, S.M. (2015). Adolescents care but don’t feel responsible for farm animal welfare. Society and Animals, 23, 269-297.


Parker, M.O., Ife, D., Ma, J., Pancholi, M., Straw, C., Smeraldi, F., Brennan, C.H. (2013). Development and automation of a test of impulse control in zebrafish. Frontiers in Systems Neuroscience, 7:65.


Redhead, E.S., Hamilton, D.A., Parker, M.O., Pitfield, C., Webber, C., Houghton, K. (2013). Overshadowing of Geometric Cues by a beacon within a spatial navigation task. Learning and Behavior, 41, 179-191.


Parker, M.O., Brock, A.J., Walton, R.T., Brennan, C.H. (2013). The role of zebrafish (Danio rerio) in dissecting the genetics and neural circuits underlying complex behavioural phenotypes. Frontiers in Neural Circuits, 7, 63.





Rice, J.P., Suggs, L.E., Lusk, A.V., Parker, M.O., Candelaria-Cook, F.T., Akers, K.G., Savage, D.D., & Hamilton, D.A. (2012). Effects of chronic intermittent exposure to moderate levels of ethanol during prenatal brain development on dendritic length, branching, and spine density in the nucleus accumbens and dorsal striatum of adult rats. Alcohol, 46, 577–584.


Parker, M.O., Brennan, C.H. (2012). Zebrafish (Danio rerio) models of substance abuse: harnessing the capabilities.Behaviour, 149, 1037 – 1062. 


Parker, M.O., Garavia, J., Haigh, A., Millington, M.E., Brown, V.J., Combe, F.J., Brennan, C.H. (2012). Discrimination Reversal and Attentional Sets in Zebrafish (Danio rerio). Behavioural Brain Research, 232, 264-268. 


Parker, M.O., Millington, M.E, Combe, F.J., & Brennan, C.H. (2012). Development and implementation of a three-choice serial reaction time task for Zebrafish (Danio rerio). Behavioural Brain Research, 227, 73-80. 


Parker, M.O., Millington, M.E., Combe, F.J., & Brennan, C.H. (2012) Housing conditions affect physiological and behavioural responses of zebrafish to the novel tank diving test. PLoS ONE, 7(4): e34992. 


Parker, M.O., Brennan, C.H. (2012). Low and Moderate alcohol consumption during pregnancy: effects on social behaviour and propensity to develop substance abuse in later life. BJOG: An International Journal of Obstetrics and Gynaecology, 119, 1671-1672.



Brennan, C.H., Parker, M.O., Millington, M.E. (2011). Using zebrafish to examine the genetics of drug seeking and impulsivity. Journal of Psychopharmacology, 25, A6.


O’Connor, EA., Parker, M.O., Demmers, TG., Lowe, JC., Owen, RC., Davey, E., Wathes CM. & Abeyesinghe, SM. (2011). The effects of low light and high noise on behavioural activity, physiological stress and production in laying hens. British Poultry Science, 52, 666-674.



Parker, M.O., O’Connor, EA., McLeman, MA., Demmers, TG., Lowe,  JC., Owen, RC., Davey, E., Wathes CM. & Abeyesinghe, SM. (2010). The impact of chronic environmental stressors on growing pigs, Sus scofra (Part 2). Social behaviour. Animal, 4, 1910-1921.


O’Connor, EA., Parker, M.O., McLeman, MA., Demmers, TG., Lowe,  JC., Owen, RC., Davey, E., Wathes CM. & Abeyesinghe, SM. (2010). The impact of chronic environmental stressors on growing pigs, Sus scofra (Part 1). Physiology, production and play behaviour. Animal, 4, 1897-1909.


Parker, M., Goodwin, D., Eager, R., Redhead, ES., Marlin, DS. (2010). Comparison of Polar® heart rate interval data with simultaneously recorded ECG signals in horses. Comparative Exercise Physiology, 6, 137-142.



Parker, M., McBride, S. D., Redhead, E., & Goodwin, D. (2009). Differential place and response learning in horses displaying an oral stereotypy. Behavioural Brain Research, 200, 100-105.



Parker, M., Redhead, E., Goodwin, D., & McBride, S. D. (2008). Impaired instrumental choice in crib-biting horses (Equus caballus). Behavioural Brain Research, 191, 137-140.


 Parker, M., Goodwin, D., & Redhead, E. (2008). Survey of breeders’ management of horses in Europe, North America and Australia: comparison of factors associated with the development of abnormal behaviour. Applied Animal Behaviour Science, 114, 206-215.




Parker, M., Goodwin, D., Redhead, E., & Mitchell, H. (2006). The effectiveness of environmental enrichment on reducing stereotypic behaviour in two captive vicugna (Vicugna vicugna). Animal Welfare, 15, 59-62.